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Multiple Choice

A 32-year-old female at 36 weeks gestation with twins experiences a seizure; on arrival she is postictal. Which condition should you suspect?

Seizures in a late-pregnancy patient, especially around 36 weeks with multifetal gestation, strongly point to eclampsia. Eclampsia is the occurrence of convulsions in the setting of preeclampsia, a hypertensive disorder of pregnancy. The postictal state confirms that a convulsive event happened, and in this clinical context it’s most likely related to a pregnancy-specific condition rather than a primary seizure disorder. Eclampsia is a obstetric emergency. Treat by ensuring airway, breathing, and circulation, administer magnesium sulfate to prevent further seizures, monitor blood pressure, and prepare for definitive management (often delivery) once stabilized, because the condition can rapidly worsen and endanger both mother and fetus. Epilepsy could cause seizures, but the pregnancy context, especially late gestation with twins, makes eclampsia much more likely. Hypoglycemia can cause seizures but is less consistent with this scenario unless glucose abnormalities are shown. Preeclampsia without seizures would not involve a seizure event, which is a key feature here.

Seizures in a late-pregnancy patient, especially around 36 weeks with multifetal gestation, strongly point to eclampsia. Eclampsia is the occurrence of convulsions in the setting of preeclampsia, a hypertensive disorder of pregnancy. The postictal state confirms that a convulsive event happened, and in this clinical context it’s most likely related to a pregnancy-specific condition rather than a primary seizure disorder.

Eclampsia is a obstetric emergency. Treat by ensuring airway, breathing, and circulation, administer magnesium sulfate to prevent further seizures, monitor blood pressure, and prepare for definitive management (often delivery) once stabilized, because the condition can rapidly worsen and endanger both mother and fetus.

Epilepsy could cause seizures, but the pregnancy context, especially late gestation with twins, makes eclampsia much more likely. Hypoglycemia can cause seizures but is less consistent with this scenario unless glucose abnormalities are shown. Preeclampsia without seizures would not involve a seizure event, which is a key feature here.